The global Liquid Nitrogen Cryopreservation Market accounted for US$ 1,805.5 Million in 2020 and is expected to arrive at US$ 4,532.5 Million by 2028 with a CAGR of 12.5% from 2021 to 2028.

Cryopreservation is an important technique for preserving biological material for lengthy period. While it is a very effective method, it uses reagents and processes that can fail if they are not used properly. The goal of cryopreservation is to retain structurally intact tissues/living cells by freezing them at extremely low temperatures. To ensure consistency, sterility, and reproducibility, the apt equipment must be in place. Prior to a standardized method of cryogenic storage, the right selection and amount of cryoprotectant agent must be supplied at the accurate temperature, and a regulated degree of freezing must be applied.

A controlled-rate freezer is used in most cellular cryopreservation systems. The liquid nitrogen in this freezing device is delivered to a closed chamber where the cell suspension is placed. Preventing fast cellular dehydration and ice crystal formation requires careful control of the freezing rate. In general, the cells are frozen at a regulated rate from ambient temperature to around 90 °C (130 °F). The frozen cell suspension is then placed in a liquid-nitrogen freezer that is kept at extremely low temperatures and has nitrogen in the vapor or liquid phase. The use of liquid-nitrogen freezers is not required for freeze-drying cryopreservation.

Market Dynamics

Liquid nitrogen is a good long-term method for keeping viable samples that maximizes energy efficiency and is environmentally beneficial. This innovative freezing method keeps cells alive and allows them to be stored indefinitely. Liquid nitrogen, on the other hand, can sustain the same low temperatures without the use of energy. At atmospheric pressures, liquid nitrogen is a naturally cryogenic fluid capable of rapidly freezing biological tissue. As a result of the naturally occurring features of liquefied atmospheric gas, it can maintain low temperatures. There are two types of liquid nitrogen storage: liquid and vapour, each with its own set of costs and benefits.

The liquid phase storage temperature is accurately maintained at –196°C. The inventory racks are submerged in liquid nitrogen, which is held in a dewar. The cells are kept in cryovials so that they don't come into direct contact with the liquid nitrogen, reducing the risk of cellular fractures while yet reaping the benefits of its intense chilling. However, there's always the chance that these vials could rupture and liquid nitrogen will leak into the box, carrying with it a slew of dangerous pathogens.

Human embryos and sperm are also frozen and stored using cryopreservation. It's notably useful for storing excess embryos produced by in vitro fertilization (IVF). Cryopreserved embryos can be used for future pregnancies or in the event that IVF with fresh embryos fails. The embryos are thawed and put into the woman's uterus during the frozen embryo transfer procedure. The use of frozen embryos is linked to a minor but significant increase in the risk of childhood cancer in children born from these embryos.

Market Insights

Application, end-use, and region are the five segments of the global liquid nitrogen cryopreservation industry. The application segment is further bifurcated into sperms, semen & testicular tissues, stem cells, embryos and oocytes, and others. Based on end-use, the segmentation includes stem cell banks, stem cell research laboratories, biotechnology & pharmaceutical organizations, contract research organizations, and research and academic institutes.

Global Liquid Nitrogen Cryopreservation Market Regional Competition

North America, Europe, Latin America, Asia-Pacific, and the Middle East & Africa are the segmentation of the global liquid nitrogen cryopreservation industry. Throughout the projected period 2021-2028, Asia-Pacific is expected to grow at the quickest rate of all regions. The favorable government business policies and the emergence of small and mid-sized firms with creative solutions are credited with this significant growth. Other Asian Pacific sectors are booming as a result of rapid industrialization and infrastructure development.

Global Liquid Nitrogen Cryopreservation Industry Segment Analysis

Application Segments

·         Stem Cells

·         Sperms, Semen & Testicular Tissues

·         Embryos and Oocytes

·         Others

End-Use Segments

·         Stem Cell Banks

·         Stem Cell Research Laboratories

·         Biotechnology & Pharmaceutical Organizations

·         Research and Academic Institutes

·         Contract Research Organizations

Liquid Nitrogen Cryopreservation Market Prominent Players

The major players in the market are identified in this section of the report. Abeyance Cryo Solutions, Antech Group Inc., BIOLOGIX GROUP LTD, CUSTOM BIOGENIC SYSTEMS, Chart Industries, Linde, Taylor-Wharton, Thermo Fisher Scientific, Inc., and Worthington Industries, Inc. are the leading players profiled in the research report.

Liquid Nitrogen Cryopreservation Market Regions

North America

·         U.S.

·         Canada

Europe

·         U.K.

·         Germany

·         France

·         Spain

·         Rest of Europe

Latin America

·         Brazil

·         Mexico

·         Rest of Latin America

Asia-Pacific

·         China

·         Japan

·         India

·         Australia

·         South Korea

·         Rest of Asia-Pacific

Middle East & Africa

·         GCC

·         South Africa

·         Rest of Middle East & Africa